Bangladesh is the second largest exporter of readymade garment (RMG) products in the world after China. Above 80% of its total export earning is contributed by the RMG sector which has a huge impact on the economy of the country. At present this RMG sector is facing many threats and challenges to hold its flourishing position because of the entrance of new competitors both in the national and international market. To overcome these challenges continuous improvement is required to a great extent. This paper experiments execution of 5S approach to a production scenario in a garments industry. 5S method should be improved to ensure ergonomics in the workplace, to reduce defects and increase cleaning and productivity growth. It is one of the fundamental tools to intensify continuous improvement process in organizations and represents a transformation in 5 steps of a job, which is characterized by maximum efficiency at the micro level and minimum loss. Any company applying the 5S methodology will have reduction of different types of waste, efficient workflow due to lesser machine breakdowns, lower defect rates, reduced inventory and effective problem visualization, visible and swift results in an efficient way.